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dolutegravir dose


Drug Intractions:

Naivex (Dolutegravir) is metabolized by UGT1A1 with only 10–15% metabolized by CYP3A4, therefore few drug interactions are expected.Naivex (Dolutegravir) is not an inducer or inhibitor of CYP450 or UGT. Naivex(dolutegravir) increases serum creatinine, it is important to recognize that the glomerular filtration rate is not affected and therefore the clinician should not be alarmed regarding metformin clinical cutoffs.

Treating #HIV infection. #Naivex (Dolutegravir) used along with other HIV medicines.

Dolutegravir is an HIV-1 integrase strand transfer inhibitor. It works by blocking #HIV-1 integrase, an enzyme needed for the #HIV virus to replicate.


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