top of page

Tivicay(Dolutegravir) 50 mg

  • Dolutegravir
  • Sep 7, 2017
  • 1 min read

Tivicay (Dolutegravir) is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity. Tivicay (Dolutegravir) has a mean EC50 value of 0.5 nM (0.21 ng/mL) to 2.1 nM (0.85 ng/mL) in peripheral blood mononuclear cells (PBMCs) and MT-4 cells.


 
 
 

Comments


RECENT POST
bottom of page